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Associate Adjunct Professor, Bioengineering & Therapeutic Sciences
Research Interests
Howard Lee, MD, PhD, is based at the Center for Drug Development Science at the UCSF campus in Washington D.C. His academic interest is in the area of drug development science. Dr. Lee has developed innovative population pharmacokinetic-pharmacodynamic models for blood pressure responses to antihypertensive drugs and for the effects of etanercept in trials of treatment of rheumatoid arthritis. Dr. Lee has worked closely with the FDA and has mentored fellows in the area of drug development.
Selected Publications
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Rea RS, Capitano B, Bies R, Bigos KL, Smith R, Lee H. Suboptimal Aminoglycoside Dosing in Critically Ill Patients, Therapeutic Drug Monitoring, 2008 (accepted for publication) |
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O'brien S, Lee H, Ritchey, AK. Once-Daily Enoxaparin in Pediatric Thromboembolism: A Dose Finding and Pharmacodynamics Study, Journal of Thrombosis and Haemostasis, May 21, 2007 |
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Yim DS, Zhou H, Buckwalter M, Nestorov I, Peck CC, Lee H. Population Pharmacokinetic Analysis and Simulation of the Time Concentration Profile of Etanercept in Pediatric Patients with Juvenile Rheumatoid Arthritis, Journal of Clinical Pharmacology, 2005;45(3):246-256
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